astrocytes in molecular layer of cerebellum after spatial learning
نویسندگان
چکیده
introduction: previous studies have suggested that the cerebellum is a primary site of motor learning. the cerebellar cortex has a particular glial architecture with large astroglial cells. in addition, more recent works have revealed that astrocytes play a more active role in neuronal activity. the aim of this study was to evaluate the number of astrocytes in the molecular layer of rat's cerebellum after spatial learning. 21 male albino wistar rats were used in this study. reference and working memory methods of morris water maze (mwm) were used. following behavioral testing, animals were decapitated under diethyl ether anesthesia. brains were removed and fixed for 2 weeks for histological assessment. finally, 7 μm thick coronal slices were cut and stained with ptah staining for showing the astrocytes. results: our results showed a significant difference in the number of astrocytes between the control, reference and working memory groups. on the other hand, the number of astrocytes in the working memory group was more than the other groups. there was no difference in density of astrocytes between the lateral and medial parts of the cerebellum in any group. it seems that the distribution of astrocytes in the lateral and medial parts of cerebellum is similar. discussion: we concluded that spatial learning such as reference or working memory methods, can increase the number of astrocytes in the cerebellum and this increase is similar in the cerebellar cortex. methods:
منابع مشابه
Astrocytes in Molecular Layer of Cerebellum after Spatial Learning
Introduction: Previous studies have suggested that the cerebellum is a primary site of motor learning. The cerebellar cortex has a particular glial architecture with large astroglial cells. In addition, more recent works have revealed that astrocytes play a more active role in neuronal activity. The aim of this study was to evaluate the number of astrocytes in the molecular layer of rat's cere...
متن کاملchange of astrocytes number in ca2 subfield of hippocampus after spatial learning
abstract: introduction & objective: the hippocampal formation is a part of limbic system that plays an important role in memory and learning. the hippocampus is divided into three subfields: ca1, ca2 and ca3. in addition to pyramidal neurons and interneurons, the astrocytes play important roles in hippocampus, probably in memory and learning. in fact, learning needs some instruments for informa...
متن کاملParasagittal zonation of GABA-B receptors in molecular layer of rat cerebellum.
Two distinct receptors mediate the effects of ~,-aminobutyric acid (GABA) in the central nervous system. GABA-A receptors, which are linked to the modulatory benzodiazepine site and chloride ion channels, are the predominant mediators of inhibitory neurotransmission in the brain. GABA-B receptors are linked to potassium and calcium channels and may act by regulation of adenylate cyclase (Bowery...
متن کاملmolecular and physiological characterizations of floral scent production in rosa damascena mill.
گل محمدی (r. damascena mill.)مهمترین گونه ای است که در تولید گلاب، عطر و اسانس، در صنعت عطرسازی و دارویی کاربرد دارد. با وجود اهمیت عطر گل محمدی، پژوهش های مولکولی و بیوشیمیایی عطر گل این گونه هنوز در مراحل ابتدایی است. در این پژوهش، ویژگی های مولکولی و فیزیولوژیکی تولید عطر در گل محمدی در آزمایش های مختلف مورد بررسی قرار گرفتند. در آزمایش اول، پژوهشی به منظور بررسی تنوع شیمیایی اسانس میان 44 ت...
منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
basic and clinical neuroscienceجلد ۳، شماره ۲، صفحات ۱۶-۲۱
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023